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π Key insights from the review: β’ Rapid growth of the field since 2019, led by the US, China, and Germany β’ Strong focus on #stroke, #Alzheimerβs disease, #Parkinsonβs disease, and bioactive compounds from traditional Chinese medicine β’ Identification of core molecular hubs: STAT3, IL6, TP53, AKT1, and JUN β’ Major mechanistic hotspots include apoptosis, NLRP3 inflammasome, microglial polarization, and NF-ΞΊB/JAK-STAT/PI3K-AKT pathways π‘ Why it matters The analysis highlights a paradigm shift away from βone drugβone targetβ approaches toward multi-target, systems-level therapeutic strategies, better aligned with the multifactorial nature of neuroinflammatory CNS diseases
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Size:1 oz
Results Timelines AOD-9604 results are modest compared to approved anti-obesity medications