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For example, taking the local pH and GSSG/2GSH ratios into consideration, cytosolic E pH7.0 = −289 mV (or even lower), mitochondrial matrix E pH7.0 = −296 mV (or even lower), and human plasma E pH7.4 = −118 mV half-cell reduction potentials ( E hc ) have been estimated [52]

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However, this calculator is intended only for injectable semaglutide supplied in a vial with the concentration clearly written in mg/mL