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High-dose use While trials have tested up to 1200mg/day (even as high as 2400mg/day) and illustrated safety, some report higher rates of gastrointestinal side effects, dizziness, and skin reactions at these levels.14 28 38 Additionally, these higher doses are often short-term (3–5 weeks) and used under clinical supervision

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The NHS Inform Scotland guidance and the Vegan Society’s recommendation align: a 10-microgram daily B12 supplement, or a 2,000-microgram weekly supplement, is enough for the vast majority of plant-based eaters

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