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Signs of Vitamin B12 Deficiency Vitamin B12 deficiency can lead to several uncomfortable symptoms, including: Constant fatigue and low energy Difficulty concentrating (brain fog) Mood swings or irritability Weakness and dizziness Tingling sensation or numbness in hands and feet If you notice these symptoms, a simple blood test can determine if you’re deficient in Vitamin B12

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Gerli et al., 1990), see Figure 1