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Ferroptosis refers to a programmed cell death process that requires iron, which differs from apoptosis, pyroptosis, and programmed necrosis

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Gut microbiota also regulated hepatic amino acid metabolism through metabolite signaling for example, aromatic amino acids (such as tryptophan and phenylalanine) undergo bacterial degradation to produce metabolites like indole and anthranilic acid, which activate cGMP-PKG and PI3K/AKT pathways [43]