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Kynurenine pathway dysregulation in major depressive disorder: the convergence of excitotoxicity, neuroinflammation, and oxidative stress | Journal of Neuroinflammation | Springer Nature Link

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Boosting NAD and NAD+ levels—either directly or through their precursors like NMN, NR, or NADH (which we’ll cover below)—may help restore cellular function, boost energy and mental clarity, support healthier aging, and protect against the stressors that become more prominent during hormonal shifts