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This process yields an excess of reactive oxygen species (ROS), which impairs endothelial function, reduces the bioavailability of nitric oxide (NO), and triggers the release of tissue factor (TF), cumulatively contributing to the formation of microclots in the pulmonary vasculature [3,4]

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Trapping can also occur as due to specialized transport systems, that "pump" substances (such as iodine) into milk