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RFK is an essential enzyme widespread in the body that transfers a phosphoryl group from ATP to riboflavin to produce flavin mononucleotide (FMN) [52], while FADS is responsible for FMN adenylation to FAD

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They can then increase the dose to 10–30 mg daily [118,119], a dose that can cause some side effects, although very rarely, including nausea, dry mouth, dizziness, headache, and heartburn [120]