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Oxidative stress is the imbalance between prooxidants and antioxidants, and this imbalance is controlled by interconnecting cascades that involve angiogenesis, hypoxia, dietary factors, and smoking/environmental exposures, among others [7,8,9,10]

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Table 6: Treatment of folate deficiency (adapted from Means 2021) 27 TOP Ongoing Care Ongoing Management Vitamin B 12 Duration of therapy Once a diagnosis of B 12 deficiency due to poor absorption of B 12 has been made, therapy should be maintained lifelong